AI trained on ape DNA predicts genetic disease risks for humans

A group of international researchers has shed further light on genetic variants responsible for human diseases by analysing primate DNA data with a novel AI algorithm. Initially, the scientists sequenced over 800 individual samples from 233 species of non-human primates representing all 16 families, from lemurs to gorillas. To interpret the data, they developed a new algorithm: PrimateAI-3D. PrimateAI-3D is built on deep-learning language architectures similar to those used in ChatGPT, but designed to model genomic rather than linguistic sequences. The team used natural selection to train its parameters, by presenting it with mutations that are ruled out for disease…

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