
Lipoproteín(a) - Lp(a) je považovaný za nezávislý rizikový faktor aterosklerózy. Jeho zvýšené koncentrácie v krvi sú spojené so zvýšenou pravdepodobnosťou srdcového zlyhania, cievnej mozgovej príhody a ďalších kardiovaskulárnych ochorení so zvýšenou celkovou úmrtnosťou. Zatiaľ nie je schválená žiadna liečba, ktorá by špecificky znižovala jeho hladinu v krvi. http://www.osel.cz/13972-dalsi-cie-prevencie-aterosklerozy-lipoprotein-a.html

Here are the answers for The New York Times Mini Crossword for March 28. https://www.cnet.com/tech/gaming/todays-nyt-mini-crossword-answers-for-friday-march-28/#ftag=CADf328eec



Article URL: https://github.com/SAT-R/sa2
Comments URL: https://news.ycombinator.com/item?id=43500769
Points: 83
# Comments: 6

Article URL: https://www.nytimes.com/2025/03/27/us/politics/pilots-signal-leak.html
Comments URL: https://news.ycombinator.com/item?id=43501821
Points: 38
# Comments: 16
https://www.nytimes.com/2025/03/27/us/politics/pilots-signal-leak.html

This article is republished with permission from Wonder Tools, a newsletter that helps you discover the most useful sites and apps. Subscribe here.
Hundreds of AI tools emerge every week. I’ve picked five new ones worth exploring. They’re free to try, easy to use, and signal new directions for useful AI.
<h2 class="wp-block-heading" id="h-1-sesame-talk-with-a-

Many schools and colleges are underperforming when it comes to sex education. Going beyond the classroom condoms-and-bananas approach, a group of students have taken it upon themselves to deliver sex ed, TikTok-style.
The TikTok account @sexedforguys, which has more than 117,000 followers, started as a school project by four students at Colby College, a private liberal arts school in Maine. Launched in 2022, the account featu

Deepak Singh, VP of Developer Agents and Experiences at AWS, helps Ryan break down the hype around agentic AI in software development. They cover the definition and real-world functionality of AI agents, how developers can integrate them into existing workflows, and the importance of establishing guardrails to ensure trust and security in agentic AI. https://stackoverflow.blog/2025/03/28/are-ai-agents-ready-for-the-enterprise/

Google’s Danny Sullivan shared what small independent sites can do to improve their rankings.
The post Google’s SEO Tips For Better Rankings – Search Central Live NYC appeared first on Search Engine Journal.
https://www.searchenginejournal.com/googles-seo-tips-for-better-rankings-search-central-live-nyc
Article URL: https://twitter.com/skdh/status/1905132853672784121
Comments URL: https://news.ycombinator.com/item?id=43498338
Points: 168
# Comments: 225

Article URL: https://rgsilva.com/blog/ps2-go-part-1/
Comments URL: https://news.ycombinator.com/item?id=43498481
Points: 25
# Comments: 0

Article URL: https://www.krayorn.com/posts/http-server-go-2/
Comments URL: https://news.ycombinator.com/item?id=43498521
Points: 12
# Comments: 0
Article URL: https://kagi.com/stats?stat=leaderboard
Comments URL: https://news.ycombinator.com/item?id=43499045
Points: 104
# Comments: 42
Article URL: http://toughsf.blogspot.com/2017/10/anti-orbit-laser-submarines.html
Comments URL: https://news.ycombinator.com/item?id=43499755
Points: 5
# Comments: 0
http://toughsf.blogspot.com/2017/10/anti-orbit-laser-submarines.html

Article URL: https://devblogs.microsoft.com/oldnewthing/20250325-00/?p=110993
Comments URL: https://news.ycombinator.com/item?id=43499823
Points: 20
# Comments: 1
https://devblogs.microsoft.com/oldnewthing/20250325-00/?p=110993


Article URL: https://blog.autorouting.com/p/13-things-i-would-have-told-myself
Comments URL: https://news.ycombinator.com/item?id=43499992
Points: 5
# Comments: 0
https://blog.autorouting.com/p/13-things-i-would-have-told-myself


This week on the PHP Podcast, Eric and John talk about Laravel Cloud, Feature Flags, PHP Tek 2025, PHPxSan, and more… Links from the show: Laravel Cloud achieves SOC 2 Type 1 Compliance – The Laravel Blog Flipt Laravel Pennant – Laravel 12.x – The PHP Framework For Web Artisans PHP[TEK] 2025 – May 20th […]
The post The PHP Podcast: 2025.03.27 appeared first on

Galaxie 2MASX J23453268−0449256 je vážně divná. Její zběsilá supermasivní černá díra chrlí rádiové jety, které měří asi 6 milionů světelných let. Přesto se galaxie, která je jednou z největších spirálních galaxií ve známém vesmíru, nezhroutila a stále se majestátně otáčí v temnotě vesmíru. http://www.osel.cz/13971-anomalni-chovani-spiralni-galaxie-vesti-budouci-potize-v-mlecne-draze.html

The White House wants to end the federal education agency, but you should still fill out FAFSA now if you want financial aid for next year. https://www.cnet.com/personal-finance/loans/whats-the-future-of-student-loans-and-fafsa-if-the-department-of-education-goes-under/#ftag=CADf328eec

Sink your teeth into the vampire ballerina flick, Abigail. https://www.cnet.com/tech/services-and-software/9-great-horror-movies-to-watch-on-prime-video-now/#ftag=CADf328eec

This water bottle is the real deal, and you can save some money on it during Amazon's Big Spring Sale. https://www.cnet.com/deals/this-stanley-tumbler-is-still-my-favorite-water-bottle-and/#ftag=CADf328eec

ChatGPT’s viral Ghibli-style image generator is not a good look for AI.

Beats Audio deals at Best Buy slash up to $170 off Apple's other best-selling headphones.

The much anticipated trailer for the next Call of Duty Zombies map 'Shattered Veil' is out now, and there's a lot to unpack .

Prakticky všechny filmy na DVD discích od Warner Bros z let 2006 až 2008 odcházejí. Warneři se k tomu stavějí čelem, nicméně ne vždy existuje uspokojivé řešení. Pomíjivost fyzických věcí se tak opět naplno ukazuje. https://www.root.cz/clanky/studiu-warner-bros-umiraji-filmy-na-dvd-a-je-to-vetsi-problem-nez-by-se-mohlo-zdat/?utm_source=rss&utm_medium=text&utm_campaign=rss

Víte, co je lepší než nový procesor? Nové znalosti! A víte, co je ještě lepší než nové znalosti? Nové znalosti, které vám zaplatí Úřad práce formou dotací. Naučíte se něco užitečného s podporou EU. https://www.root.cz/clanky/dotace-na-it-kurzy-nechte-eu-zaplatit-za-vase-vzdelani-a-usetrete-rodinny-rozpocet/?utm_source=rss&utm_medium=text&utm_campaign=rss
Article URL: https://www.di.ens.fr/~fbach/ltfp_book.pdf
Comments URL: https://news.ycombinator.com/item?id=43497954
Points: 42
# Comments: 2

Article URL: https://sgnly.com
Comments URL: https://news.ycombinator.com/item?id=43498031
Points: 19
# Comments: 30

Article URL: https://www.scottsmitelli.com/articles/take-oncall-and-shove-it/
Comments URL: https://news.ycombinator.com/item?id=43498213
Points: 84
# Comments: 30
https://www.scottsmitelli.com/articles/take-oncall-and-shove-it/


Article URL: https://www.rahuljuliato.com/posts/emacs-solo-demo
Comments URL: https://news.ycombinator.com/item?id=43498696
Points: 6
# Comments: 0
Article URL: https://reviews.ofb.biz/safari/article/1300.html
Comments URL: https://news.ycombinator.com/item?id=43498984
Points: 99
# Comments: 46

As the global auto world reeled from the potential fallout of Donald Trump‘s new auto tariffs, one name stood out as less affected than others—electric-vehicle maker Tesla.
The Texas-based company’s shares were the rare automotive sto

CoreWeave plans to reduce the size of its U.S. initial public offering and price its shares below the indicated range, a person familiar with the matter told Reuters on Thursday, dampening expectations that the listing would boost investor appetite for IPOs.
The Nvidia-backed cloud services provider is now looking to sell 37.5 million shares, 23.5% less than originally planned, and price them at $40 apiece, well below even

My love of this portable cooktop burner is real. And now you can get a massive discount on it during Amazon's Spring Sale. https://www.cnet.com/deals/this-portable-induction-cooktop-burner-saved-me-during-a-kitchen-remodel-and-its-20-off-for-amazons-spring-sale/#ftag=CADf328eec

Stop making these errors to start your morning with a fantastic cup of coffee. https://www.cnet.com/news/dont-ruin-your-coffee-expert-micro-roaster-shares-biggest-home-brewing-mistakes/#ftag=CADf328eec

I travel a lot, and the Insta360 Go 3S is my favorite 4K camera to bring with me. It just received a big discount for Amazon's Spring Sale. https://www.cnet.com/deals/want-cool-travel-pics-my-favorite-tiny-4k-camera-is-60-off-on-amazon/#ftag=CADf328eec

Alongside new field upgrades and score streaks, the zombies map coming in season 3 will have a perk not seen since Black Ops Cold War. https://www.cnet.com/tech/gaming/black-ops-6-adds-two-classic-wonder-weapons-and-a-new-map-shattered-veil/#ftag=CADf328eec

Here are hints and answers for the NYT Strands puzzle No. 390 for March 28. https://www.cnet.com/tech/gaming/todays-nyt-strands-hints-answers-and-help-for-march-28-390/#ftag=CADf328eec

Hints and answers for the NYT Connections: Sports Edition puzzle, No. 186, for March 28. https://www.cnet.com/tech/gaming/todays-nyt-connections-sports-edition-hints-and-answers-for-march-28-186/#ftag=CADf328eec

Here are hints and the answer for today's Wordle No. 1,378 for March 28. https://www.cnet.com/tech/gaming/todays-wordle-hints-answer-and-help-for-march-28-1378/#ftag=CADf328eec

Those in states bordering Canada will have the best chance. https://www.cnet.com/science/aurora-borealis-forecast-is-trending-but-only-the-northern-states-will-see-anything/#ftag=CADf328eec

Rhythm Heaven and Tomodachi Life are coming back. https://www.cnet.com/tech/gaming/nintendo-revived-two-dormant-game-franchises-for-new-switch-titles/#ftag=CADf328eec

Make the cutest breakfast at some of the tiniest prices so far this year, thanks to Amazon Big Spring Sale deals on Peeps x Dash kitchen accessories. https://www.cnet.com/tech/add-an-adorable-touch-to-your-kitchen-with-these-peeps-x-dash-accessories-for-as-low-as-10/#ftag=CADf328eec

OpenAI CEO Sam Altman tweeted that there will be temporary rate limits while the company works on improving efficiency. https://www.cnet.com/tech/services-and-software/chatgpts-gpus-are-melting-as-people-make-studio-ghibli-esque-ai-images/#ftag=CADf328eec

It's not working for everyone yet, but a company spokesperson says all subscribers should have access Thursday. https://www.cnet.com/tech/services-and-software/instagram-launching-ability-to-play-reels-at-2x-speed/#ftag=CADf328eec

Actor Olivier Richters, aka The Dutch Giant, gives me the lowdown on the show's high-adrenaline fight scene. Making the scene happen wasn't exactly a walk in the park. https://www.cnet.com/tech/services-and-software/inside-the-reacher-season-3-finales-bone-breaking-brawl-the-dutch-giant-speaks/#ftag=CADf328eec

Apple Watch owners, you may be eligible for part of the large cash settlement -- check this list of affected models. https://www.cnet.com/tech/mobile/dont-miss-deadline-to-claim-your-share-of-the-20-million-apple-watch-payout-before-time-runs-out/#ftag=CADf328eec

Nvidia NIM microservices are designed to help you run AI on your local device, allowing you to do more with AI models. https://www.cnet.com/tech/services-and-software/nvidias-new-tools-make-running-ai-on-your-computer-a-breeze/#ftag=CADf328eec

Is it still Girl Scout cookie time? That's a hint to the answer for Connections for March 28, #656. https://www.cnet.com/tech/gaming/todays-nyt-connections-hints-answers-and-help-for-march-28-656/#ftag=CADf328eec

HP ZBook Ultra G1a delivers AI-powered performance with a 16-core Ryzen AI Max+ Pro 395, 128GB RAM, and a high-speed 2TB SSD.

Our first look at the Joy-Cons "C" button

Nintendo just revealed the Virtual Game Card for the Nintendo Switch, and let me tell you why this might be more revolutionary than the Switch 2.
https://www.laptopmag.com/gaming/nintendo-virtual-game-card-feature-switch-2

Save $470 on the MSI Thin A15 in this limited-time Newegg Super Spring Sale deal.

Unnannounced Hogwarts Legacy DLC reportedly canceled by WB Games, according to a new report.
https://www.windowscentral.com/gaming/hogwarts-legacy-dlc-definitive-edition-reportedly-canceled

If Helldivers 2 players can complete this new Major Order, the Illuminate's Meridian Singularity black hole can finally be stopped.

After a slow, five-year build of its first U.S. fab due to labor and logistical hurdles, TSMC now plans to construct future U.S. facilities in two years, but can its timely access to chipmaking equipment remains an uncertainty.

Shadow Labyrinth, an utterly bonkers riff on Pac-Man and sidescrolling Metroidvania games, will hit digital store shelves on July 18. It’ll be available for Nintendo Switch, PC via

In the final days of our pre-Switch 2 world, Nintendo is trying to rethink how sharing games works. The biggest announcement from the company's latest Direct was its upcoming

There's a lot in the world to be angry about today. So, why not do like we did in the '90s and channel that aggression into beating the living hell out of bad guys in a delightfully loud and over-the-top arcade game? Marvel Cosmic Invasion takes characters like Spider-Man, Captain America and Wolverine and gives them a beat-'em-up that looks straight out of a grunge-era cabinet.

The Amazon Spring Sale has made me jealous — I'm envious of those who can now pick up

Anker power banks and other charging gear have been discounted thanks to the Amazon Spring Sale. Noteworthy among the deals is this

This year’s Amazon Spring Sale is in full swing, and as promised, a ton of household, fashion and outdoor gear has dropped to record-low prices. Tech isn’t a huge focus for this sale, but there are a decent number of devices on sale right now for some of the best prices we’ve seen all year. The selection may not be as good as that of Amazon Prime Day in July, but it still provides a good opportunity to save on
Article URL: https://phys.org/news/2025-03-bias-social-tinny-video-conferences.html
Comments URL: https://news.ycombinator.com/item?id=43495465
Points: 71
# Comments: 73
https://phys.org/news/2025-03-bias-social-tinny-video-conferences.html

Article URL: https://github.com/inko-lang/inko
Comments URL: https://news.ycombinator.com/item?id=43496355
Points: 10
# Comments: 2
Article URL: https://blog.zksecurity.xyz/posts/clean/
Comments URL: https://news.ycombinator.com/item?id=43496577
Points: 27
# Comments: 2
Article URL: https://www.science.org/content/article/ai-models-miss-disease-black-female-patients
Comments URL: https://news.ycombinator.com/item?id=43496644
Points: 141
# Comments: 119
https://www.science.org/content/article/ai-models-miss-disease-black-female-patients

Article URL: https://www.wired.com/story/signalgate-is-driving-the-most-us-downloads-of-signal-ever/
Comments URL: https://news.ycombinator.com/item?id=43497150
Points: 78
# Comments: 39
https://www.wired.com/story/signalgate-is-driving-the-most-us-downloads-of-signal-ever/

Article URL: https://citizenlab.ca/2024/11/analysis-of-censorship-on-amazon-com/
Comments URL: https://news.ycombinator.com/item?id=43497264
Points: 23
# Comments: 4
https://citizenlab.ca/2024/11/analysis-of-censorship-on-amazon-com/

Article URL: https://victorpoughon.fr/i-tried-making-artificial-sunlight-at-home/
Comments URL: https://news.ycombinator.com/item?id=43497394
Points: 81
# Comments: 29
https://victorpoughon.fr/i-tried-making-artificial-sunlight-at-home/
Article URL: http://archimago.blogspot.com/2025/03/hdmi-musings-high-speed-cables-data.html
Comments URL: https://news.ycombinator.com/item?id=43497398
Points: 7
# Comments: 1
http://archimago.blogspot.com/2025/03/hdmi-musings-high-speed-cables-data.html

Article URL: https://www.merriam-webster.com/grammar/em-dash-en-dash-how-to-use
Comments URL: https://news.ycombinator.com/item?id=43497719
Points: 28
# Comments: 19
https://www.merriam-webster.com/grammar/em-dash-en-dash-how-to-use

dish is a lightweight, 0 dependency monitoring tool in the form of a small binary executable. Upon execution, it checks the provided sockets (which can be provided in a JSON file or served by a remote JSON API endpoint). The results of the check are then reported to the configured channels.
It started as a learning project and ended up proving quite handy. Me and my friend have been using it to monitor our services for the last 3 years.
We have refactored the codebase to be a bit more pr


Article URL: https://www.ycombinator.com/companies/revyl/jobs/5rbIJLP-frontend-engineer-intern
Comments URL: https://news.ycombinator.com/item?id=43498109
Points: 0
# Comments: 0
https://www.ycombinator.com/companies/revyl/jobs/5rbIJLP-frontend-engineer-intern

Smartphones have been around long enough that, to the casual observer, their designs seem to have hit a plateau. And on a functional level, that’s more or less true—we’re all essentially holding the same six-inch-ish rectangle, aside from the occasional foldable exception.
But the maturity and ubiquity of smartphones have sparked a new phenomenon: the return of trends in cycles, much like fashion. For example, most phone

X owner Elon Musk was privately messaging with Reddit CEO Steve Huffman while also putting public pressure on the social media company’s content moderation efforts, The Verge reported Thursday.
Two months ago, several Reddit subreddits started to

I use Apple AirTags to track pretty much everything I own. Right now, you can get a four-pack for nearly 30% off. https://www.cnet.com/deals/if-you-need-multiple-apple-airtags-this-4-pack-is-30-off-for-amazons-big-spring-sale/#ftag=CADf328eec

Virtual Game Cards are coming, and they'll work across systems and family accounts, and on both the Switch and Switch 2. Here's what we know so far. https://www.cnet.com/videos/nintendos-allowing-digital-game-sharing-heres-what-that-means-and-how-it-works/#ftag=CADf328eec

Skyworth's 24-inch portable TV with a built-in battery normally isn't cheap for a 24-inch TV, but it's currently $100 off on Amazon. https://www.cnet.com/deals/i-found-the-perfect-portable-tv-for-my-patio-and-its-25-percent-off-during-amazons-big-spring-sale/#ftag=CADf328eec

Green tea has several hidden health benefits. If you're ready to cut down on coffee, here's why you should switch your choice of morning beverage. https://www.cnet.com/health/nutrition/take-advantage-of-green-teas-hidden-benefits-for-focus-and-calm/#ftag=CADf328eec

Alpaka bags are known for their rugged construction and durability. You can snag one of these top quality bag for up to half off if you're an Amazon Prime Member. https://www.cnet.com/tech/prime-members-save-up-to-50-on-alpaka-bags-during-amazons-big-spring-sale/#ftag=CADf328eec

Made famous on TikTok and YouTube, the hit viral series will air live. https://www.cnet.com/tech/services-and-software/pop-the-balloon-dating-show-is-coming-to-netflix-in-april/#ftag=CADf328eec

Even if you think you're washing your towels enough, the chances are high that you probably aren't. https://www.cnet.com/how-to/dirty-little-secret-heres-how-often-you-should-wash-your-bath-towels/#ftag=CADf328eec

Reports say the SSA workforce reductions are making it harder for Social Security beneficiaries to contact the organization or access their account online. https://www.cnet.com/personal-finance/post-layoffs-recipients-are-having-trouble-contacting-the-ssa/#ftag=CADf328eec

Are you thinking of cutting the cord? Here's why my go-to streaming stick is a steal during Amazon's Big Spring Sale. https://www.cnet.com/tech/roku-streaming-4k-stick-the-best-prime-pick-of-amazons-big-spring-sale/#ftag=CADf328eec

Now's the time to stock up on a wide selection of discounted 4K Blu-rays during Amazon's Spring Sale. https://www.cnet.com/tech/score-big-discounts-on-4k-blu-ray-box-sets-during-amazons-spring-sale/#ftag=CADf328eec

The OpenAI Bug Bounty Program just got five times more lucrative.